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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBC1D1 All Species: 13.33
Human Site: Y625 Identified Species: 48.89
UniProt: Q86TI0 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86TI0 NP_055988.2 1168 133084 Y625 S Q R K L M R Y H S V S T E T
Chimpanzee Pan troglodytes XP_001137680 1168 132983 Y625 S Q R K L M R Y H S V S T E T
Rhesus Macaque Macaca mulatta XP_001087581 1169 132693 Y625 S Q R K L M R Y H S V S T E T
Dog Lupus familis XP_863618 1170 132449 Y626 S Q R K F M R Y H S V S T E T
Cat Felis silvestris
Mouse Mus musculus Q60949 1255 142006 D712 L K F L A P V D E N N T C D F
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513119 1090 120577 L601 I L Q Q I L L L R M E K E N R
Chicken Gallus gallus Q5ZJ17 816 92547 I327 L S N K E L A I E R C F G M L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.1 90.7 N.A. 83.9 N.A. N.A. 55.4 22.7 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.5 98.8 94.6 N.A. 87.4 N.A. N.A. 65.4 38.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 0 N.A. N.A. 0 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 26.6 N.A. N.A. 26.6 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 15 0 15 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 15 0 15 0 0 % C
% Asp: 0 0 0 0 0 0 0 15 0 0 0 0 0 15 0 % D
% Glu: 0 0 0 0 15 0 0 0 29 0 15 0 15 58 0 % E
% Phe: 0 0 15 0 15 0 0 0 0 0 0 15 0 0 15 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % G
% His: 0 0 0 0 0 0 0 0 58 0 0 0 0 0 0 % H
% Ile: 15 0 0 0 15 0 0 15 0 0 0 0 0 0 0 % I
% Lys: 0 15 0 72 0 0 0 0 0 0 0 15 0 0 0 % K
% Leu: 29 15 0 15 43 29 15 15 0 0 0 0 0 0 15 % L
% Met: 0 0 0 0 0 58 0 0 0 15 0 0 0 15 0 % M
% Asn: 0 0 15 0 0 0 0 0 0 15 15 0 0 15 0 % N
% Pro: 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 58 15 15 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 58 0 0 0 58 0 15 15 0 0 0 0 15 % R
% Ser: 58 15 0 0 0 0 0 0 0 58 0 58 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 15 58 0 58 % T
% Val: 0 0 0 0 0 0 15 0 0 0 58 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 58 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _